This follows on "Ancient Roman environment" paragraph halfway down here: the blog post about the Roman road network ended up observing the vastly different water regime in ancient Mesopotamia.
Fox News Digital ran a feature titled Alexander the Great's long-lost city located after nearly two millennia: ‘Absolutely stunning’ about Alexandria-on-the-Tigris (Charax Spasinou, summary at bottom). That falls smack dab in the middle of that map region. I simply recycled the previous map with Ancient World Mapping Center (AWMC) at UNC-Chapel Hill data for that period.